1 Study Coverage 1.1 Esketamine Product Introduction 1.2 Global Esketamine Outlook 2017 VS 2022 VS 2028 1.2.1 Global Esketamine Sales in US$ Million for the Year 2017-2028 1.2.2 Global Esketamine Sales in Volume for the Year 2017-2028 1.3 United States Esketamine Outlook 2017 VS 2022 VS 2028 1.3.1 United States Esketamine Sales in US$ Million for the Year 2017-2028 1.3.2 United States Esketamine Sales in Volume for the Year 2017-2028 1.4 Esketamine Market Size, United States VS Global, 2017 VS 2022 VS 2028 1.4.1 The Market Share of United States Esketamine in Global, 2017 VS 2022 VS 2028 1.4.2 The Growth Rate of Esketamine Market Size, United States VS Global, 2017 VS 2022 VS 2028 1.5 Esketamine Market Dynamics 1.5.1 Esketamine Industry Trends 1.5.2 Esketamine Market Drivers 1.5.3 Esketamine Market Challenges 1.5.4 Esketamine Market Restraints 1.6 Study Objectives 1.7 Years Considered 2 Market by Type 2.1 Esketamine Market Segment by Type 2.1.1 Oral Medications 2.1.2 Injection 2.1.3 Nasal Spray 2.2 Global Esketamine Market Size by Type 2.2.1 Global Esketamine Sales in Value, by Type (2017, 2022 & 2028) 2.2.2 Global Esketamine Sales in Volume, by Type (2017, 2022 & 2028) 2.2.3 Global Esketamine Average Selling Price (ASP) by Type (2017, 2022 & 2028) 2.3 United States Esketamine Market Size by Type 2.3.1 United States Esketamine Sales in Value, by Type (2017, 2022 & 2028) 2.3.2 United States Esketamine Sales in Volume, by Type (2017, 2022 & 2028) 2.3.3 United States Esketamine Average Selling Price (ASP) by Type (2017, 2022 & 2028) 3 Market by Application 3.1 Esketamine Market Segment by Application 3.1.1 General Anesthetic 3.1.2 Treatment-resistant Depression 3.2 Global Esketamine Market Size by Application 3.2.1 Global Esketamine Sales in Value, by Application (2017, 2022 & 2028) 3.2.2 Global Esketamine Sales in Volume, by Application (2017, 2022 & 2028) 3.3.3 Global Esketamine Average Selling Price (ASP) by Application (2017, 2022 & 2028) 3.3 United States Esketamine Market Size by Application 3.3.1 United States Esketamine Sales in Value, by Application (2017, 2022 & 2028) 3.3.2 United States Esketamine Sales in Volume, by Application (2017, 2022 & 2028) 3.3.3 United States Esketamine Average Selling Price (ASP) by Application (2017, 2022 & 2028) 4 Global Esketamine Competitor Landscape by Company 4.1 Global Esketamine Market Size by Company 4.1.1 Top Global Esketamine Manufacturers Ranked by Revenue (2021) 4.1.2 Global Esketamine Revenue by Manufacturer (2017-2022) 4.1.3 Global Esketamine Sales by Manufacturer (2017-2022) 4.1.4 Global Esketamine Price by Manufacturer (2017-2022) 4.2 Global Esketamine Concentration Ratio (CR) 4.2.1 Esketamine Market Concentration Ratio (CR) (2017-2022) 4.2.2 Global Top 5 and Top 10 Largest Manufacturers of Esketamine in 2021 4.2.3 Global Esketamine Market Share by Company Type (Tier 1, Tier 2, and Tier 3) 4.3 Global Esketamine Manufacturing Base Distribution, Product Type 4.3.1 Global Esketamine Manufacturers, Headquarters and Distribution of Producing Region 4.3.2 Manufacturers Esketamine Product Type 4.3.3 Date of International Manufacturers Enter into Esketamine Market 4.4 Manufacturers Mergers & Acquisitions, Expansion Plans 4.5 United States Esketamine Market Size by Company 4.5.1 Top Esketamine Players in United States, Ranked by Revenue (2021) 4.5.2 United States Esketamine Revenue by Players (2020, 2021 & 2022) 4.5.3 United States Esketamine Sales by Players (2020, 2021 & 2022) 5 Global Esketamine Market Size by Region 5.1 Global Esketamine Market Size by Region: 2017 VS 2022 VS 2028 5.2 Global Esketamine Market Size in Volume by Region (2017-2028) 5.2.1 Global Esketamine Sales in Volume by Region: 2017-2022 5.2.2 Global Esketamine Sales in Volume Forecast by Region (2023-2028) 5.3 Global Esketamine Market Size in Value by Region (2017-2028) 5.3.1 Global Esketamine Sales in Value by Region: 2017-2022 5.3.2 Global Esketamine Sales in Value by Region: 2023-2028 6 Segment in Region Level & Country Level 6.1 North America 6.1.1 North America Esketamine Market Size YoY Growth 2017-2028 6.1.2 North America Esketamine Market Facts & Figures by Country (2017, 2022 & 2028) 6.1.3 U.S. 6.1.4 Canada 6.2 Asia-Pacific 6.2.1 Asia-Pacific Esketamine Market Size YoY Growth 2017-2028 6.2.2 Asia-Pacific Esketamine Market Facts & Figures by Region (2017, 2022 & 2028) 6.2.3 China 6.2.4 Japan 6.2.5 South Korea 6.2.6 India 6.2.7 Australia 6.2.8 Taiwan 6.2.9 Indonesia 6.2.10 Thailand 6.2.11 Malaysia 6.2.12 Philippines 6.3 Europe 6.3.1 Europe Esketamine Market Size YoY Growth 2017-2028 6.3.2 Europe Esketamine Market Facts & Figures by Country (2017, 2022 & 2028) 6.3.3 Germany 6.3.4 France 6.3.5 U.K. 6.3.6 Italy 6.3.7 Russia 6.4 Latin America 6.4.1 Latin America Esketamine Market Size YoY Growth 2017-2028 6.4.2 Latin America Esketamine Market Facts & Figures by Country (2017, 2022 & 2028) 6.4.3 Mexico 6.4.4 Brazil 6.4.5 Argentina 6.5 Middle East and Africa 6.5.1 Middle East and Africa Esketamine Market Size YoY Growth 2017-2028 6.5.2 Middle East and Africa Esketamine Market Facts & Figures by Country (2017, 2022 & 2028) 6.5.3 Turkey 6.5.4 Saudi Arabia 6.5.5 U.A.E 7 Company Profiles 7.1 Merck 7.1.1 Merck Corporation Information 7.1.2 Merck Description and Business Overview 7.1.3 Merck Esketamine Sales, Revenue and Gross Margin (2017-2022) 7.1.4 Merck Esketamine Products Offered 7.1.5 Merck Recent Development 7.2 Medkoo 7.2.1 Medkoo Corporation Information 7.2.2 Medkoo Description and Business Overview 7.2.3 Medkoo Esketamine Sales, Revenue and Gross Margin (2017-2022) 7.2.4 Medkoo Esketamine Products Offered 7.2.5 Medkoo Recent Development 7.3 Endo International 7.3.1 Endo International Corporation Information 7.3.2 Endo International Description and Business Overview 7.3.3 Endo International Esketamine Sales, Revenue and Gross Margin (2017-2022) 7.3.4 Endo International Esketamine Products Offered 7.3.5 Endo International Recent Development 7.4 Janssen Pharmaceutica 7.4.1 Janssen Pharmaceutica Corporation Information 7.4.2 Janssen Pharmaceutica Description and Business Overview 7.4.3 Janssen Pharmaceutica Esketamine Sales, Revenue and Gross Margin (2017-2022) 7.4.4 Janssen Pharmaceutica Esketamine Products Offered 7.4.5 Janssen Pharmaceutica Recent Development 7.5 PFIZER 7.5.1 PFIZER Corporation Information 7.5.2 PFIZER Description and Business Overview 7.5.3 PFIZER Esketamine Sales, Revenue and Gross Margin (2017-2022) 7.5.4 PFIZER Esketamine Products Offered 7.5.5 PFIZER Recent Development 8 Industry Chain and Sales Channels Analysis 8.1 Esketamine Industry Chain Analysis 8.2 Esketamine Key Raw Materials 8.2.1 Key Raw Materials 8.2.2 Esketamine Distributors 8.3 Esketamine Production Mode & Process 8.4 Esketamine Sales and Marketing 8.4.1 Esketamine Sales Channels 8.4.2 Esketamine Distributors 8.5 Esketamine Customers 9 Research Findings and Conclusion 10 Appendix 10.1 Research Methodology 10.1.1 Methodology/Research Approach 10.1.2 Data Source 10.2 Author Details 10.3 Disclaimer

List of Tables Table 1. Esketamine CAGR in Value, United States VS Global, 2017 VS 2022 VS 2028 Table 2. Esketamine Market Trends Table 3. Esketamine Market Drivers Table 4. Esketamine Market Challenges Table 5. Esketamine Market Restraints Table 6. Global Esketamine Sales by Type: 2017 VS 2022 VS 2028 (US$ Million) Table 7. United States Esketamine Sales by Type: 2017 VS 2022 VS 2028 (US$ Million) Table 8. Global Esketamine Sales by Application: 2017 VS 2022 VS 2028 (US$ Million) Table 9. United States Esketamine Sales by Application: 2017 VS 2022 VS 2028 (US$ Million) Table 10. Top Esketamine Manufacturers in Global Market, Ranking by Revenue (2021) Table 11. Global Esketamine Revenue by Manufacturer, (US$ Million), 2017-2022 Table 12. Global Esketamine Revenue Share by Manufacturer, 2017-2022 Table 13. Global Esketamine Sales by Manufacturer, (K Units), 2017-2022 Table 14. Global Esketamine Sales Share by Manufacturer, 2017-2022 Table 15. Global Esketamine Price by Manufacturer (2017-2022) & (USD/Unit) Table 16. Global Esketamine Manufacturers Market Concentration Ratio (CR5 and HHI) Table 17. Global Esketamine by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Esketamine as of 2021) Table 18. Top Players of Esketamine in Global Market, Headquarters and Distribution of Producing Region Table 19. Manufacturers Esketamine Product Type Table 20. Date of International Manufacturers Enter into Esketamine Market Table 21. Manufacturers Mergers & Acquisitions, Expansion Plans Table 22. Top Esketamine Players in United States Market, Ranking by Revenue (2021) Table 23. United States Esketamine Revenue by Players, (US$ Million), 2020, 2021 & 2022 Table 24. United States Esketamine Revenue Share by Players, 2020, 2021 & 2022 Table 25. United States Esketamine Sales by Players, (K Units), 2020, 2021 & 2022 Table 26. United States Esketamine Sales Share by Players, 2020, 2021 & 2022 Table 27. Global Esketamine Market Size by Region (US$ Million): 2017 VS 2022 VS 2028 Table 28. Global Esketamine Sales in Volume by Region (2017-2022) & (K Units) Table 29. Global Esketamine Sales in Volume Forecast by Region (2023-2028) & (K Units) Table 30. Global Esketamine Sales in Value by Region (2017-2022) & (US$ Million) Table 31. Global Esketamine Sales in Value Forecast by Region (2023-2028) & (US$ Million) Table 32. North America Esketamine Sales in Volume by Country (2017-2028) & (K Units) Table 33. North America Esketamine Sales in Value by Country (2017-2028) & (US$ Million) Table 34. Asia Pacific Esketamine Sales in Volume by Region (2017-2028) & (K Units) Table 35. Asia Pacific Esketamine Sales in Value by Region (2017-2028) & (US$ Million) Table 36. Europe Esketamine Sales in Volume by Country (2017-2028) & (K Units) Table 37. Europe Esketamine Sales in Value by Country (2017-2028) & (US$ Million) Table 38. Latin America Esketamine Sales in Volume by Country (2017-2028) & (K Units) Table 39. Latin Americaa Esketamine Sales in Value by Country (2017-2028) & (US$ Million) Table 40. Middle East and Africa Esketamine Sales in Volume by Country (2017-2028) & (K Units) Table 41. Middle East and Africa Esketamine Sales in Value by Country (2017-2028) & (US$ Million) Table 42. Merck Corporation Information Table 43. Merck Description and Business Overview Table 44. Merck Esketamine Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022) Table 45. Merck Esketamine Product Table 46. Merck Recent Development Table 47. Medkoo Corporation Information Table 48. Medkoo Description and Business Overview Table 49. Medkoo Esketamine Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022) Table 50. Medkoo Product Table 51. Medkoo Recent Development Table 52. Endo International Corporation Information Table 53. Endo International Description and Business Overview Table 54. Endo International Esketamine Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022) Table 55. Endo International Product Table 56. Endo International Recent Development Table 57. Janssen Pharmaceutica Corporation Information Table 58. Janssen Pharmaceutica Description and Business Overview Table 59. Janssen Pharmaceutica Esketamine Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022) Table 60. Janssen Pharmaceutica Product Table 61. Janssen Pharmaceutica Recent Development Table 62. PFIZER Corporation Information Table 63. PFIZER Description and Business Overview Table 64. PFIZER Esketamine Sales (K Units), Revenue (US$ Million), Price (USD/Unit) and Gross Margin (2017-2022) Table 65. PFIZER Product Table 66. PFIZER Recent Development Table 67. Key Raw Materials Lists Table 68. Raw Materials Key Suppliers Lists Table 69. Esketamine Customers List Table 70. Esketamine Distributors List Table 71. Research Programs/Design for This Report Table 72. Key Data Information from Secondary Sources Table 73. Key Data Information from Primary Sources List of Figures Figure 1. Esketamine Product Picture Figure 2. Global Esketamine Revenue, (US$ Million), 2017 VS 2022 VS 2028 Figure 3. Global Esketamine Market Size 2017-2028 (US$ Million) Figure 4. Global Esketamine Sales 2017-2028 (K Units) Figure 5. United States Esketamine Revenue, (US$ Million), 2017 VS 2022 VS 2028 Figure 6. United States Esketamine Market Size 2017-2028 (US$ Million) Figure 7. United States Esketamine Sales 2017-2028 (K Units) Figure 8. United States Esketamine Market Share in Global, in Value (US$ Million) 2017-2028 Figure 9. United States Esketamine Market Share in Global, in Volume (K Units) 2017-2028 Figure 10. Esketamine Report Years Considered Figure 11. Product Picture of Oral Medications Figure 12. Product Picture of Injection Figure 13. Product Picture of Nasal Spray Figure 14. Global Esketamine Market Share by Type in 2022 & 2028 Figure 15. Global Esketamine Sales in Value by Type (2017-2028) & (US$ Million) Figure 16. Global Esketamine Sales Market Share in Value by Type (2017-2028) Figure 17. Global Esketamine Sales by Type (2017-2028) & (K Units) Figure 18. Global Esketamine Sales Market Share in Volume by Type (2017-2028) Figure 19. Global Esketamine Price by Type (2017-2028) & (USD/Unit) Figure 20. United States Esketamine Market Share by Type in 2022 & 2028 Figure 21. United States Esketamine Sales in Value by Type (2017-2028) & (US$ Million) Figure 22. United States Esketamine Sales Market Share in Value by Type (2017-2028) Figure 23. United States Esketamine Sales by Type (2017-2028) & (K Units) Figure 24. United States Esketamine Sales Market Share in Volume by Type (2017-2028) Figure 25. United States Esketamine Price by Type (2017-2028) & (USD/Unit) Figure 26. Product Picture of General Anesthetic Figure 27. Product Picture of Treatment-resistant Depression Figure 28. Global Esketamine Market Share by Application in 2022 & 2028 Figure 29. Global Esketamine Sales in Value by Application (2017-2028) & (US$ Million) Figure 30. Global Esketamine Sales Market Share in Value by Application (2017-2028) Figure 31. Global Esketamine Sales by Application (2017-2028) & (K Units) Figure 32. Global Esketamine Sales Market Share in Volume by Application (2017-2028) Figure 33. Global Esketamine Price by Application (2017-2028) & (USD/Unit) Figure 34. United States Esketamine Market Share by Application in 2022 & 2028 Figure 35. United States Esketamine Sales in Value by Application (2017-2028) & (US$ Million) Figure 36. United States Esketamine Sales Market Share in Value by Application (2017-2028) Figure 37. United States Esketamine Sales by Application (2017-2028) & (K Units) Figure 38. United States Esketamine Sales Market Share in Volume by Application (2017-2028) Figure 39. United States Esketamine Price by Application (2017-2028) & (USD/Unit) Figure 40. North America Esketamine Sales in Volume Growth Rate 2017-2028 (K Units) Figure 41. North America Esketamine Sales in Value Growth Rate 2017-2028 (US$ Million) Figure 42. U.S. Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 43. Canada Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 44. Europe Esketamine Sales in Volume Growth Rate 2017-2028 (K Units) Figure 45. Europe Esketamine Sales in Value Growth Rate 2017-2028 (US$ Million) Figure 46. Germany Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 47. France Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 48. U.K. Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 49. Italy Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 50. Russia Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 51. Asia-Pacific Esketamine Sales in Volume Growth Rate 2017-2028 (K Units) Figure 52. Asia-Pacific Esketamine Sales in Value Growth Rate 2017-2028 (US$ Million) Figure 53. China Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 54. Japan Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 55. South Korea Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 56. India Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 57. Australia Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 58. Taiwan Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 59. Indonesia Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 60. Thailand Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 61. Malaysia Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 62. Philippines Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 63. Latin America Esketamine Sales in Volume Growth Rate 2017-2028 (K Units) Figure 64. Latin America Esketamine Sales in Value Growth Rate 2017-2028 (US$ Million) Figure 65. Mexico Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 66. Brazil Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 67. Argentina Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 68. Middle East & Africa Esketamine Sales in Volume Growth Rate 2017-2028 (K Units) Figure 69. Middle East & Africa Esketamine Sales in Value Growth Rate 2017-2028 (US$ Million) Figure 70. Turkey Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 71. Saudi Arabia Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 72. U.A.E Esketamine Sales in Value Growth Rate (2017-2028) & (US$ Million) Figure 73. Esketamine Value Chain Figure 74. Esketamine Production Process Figure 75. Channels of Distribution Figure 76. Distributors Profiles Figure 77. Bottom-up and Top-down Approaches for This Report Figure 78. Data Triangulation Figure 79. Key Executives Interviewed

Merck Medkoo Endo International Janssen Pharmaceutica PFIZER